Life with Diabetes

DKA: Signs, Symptoms, and Treatment

Diabetic ketoacidosis (DKA) is a serious and potentially life-threatening complication of diabetes that can develop quickly. Learn what to do if you are in DKA and how to prevent it in the future.  

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Photograph: Woman on couch, wrapped in blanket, holding head and water glass, looking distressed.

What is DKA?

DKA occurs when ketones in your blood make it too acidic. Ketones develop when your body doesn’t have enough insulin to use blood glucose for energy. Instead, it breaks down fat for energy, producing ketones. As ketones build up in your blood, it becomes dangerously acidic, which can affect how your body functions, make you sick, and become life-threatening if it’s not treated. DKA can affect all people living with diabetes—especially during illness, infection, missed insulin doses, or when taking certain medications. Understanding the warning signs and acting quickly can help protect your health.

Ketones vs. DKA:

  • Ketones: An early warning sign that your body is breaking down fat for energy—this is most likely to happen if you’re taking insulin, an SGLT2 inhibitor, or certain other diabetes medications
  • DKA: A life-threatening condition that occurs when ketones build up to dangerous levels. 

What You Need to Know About DKA

  • DKA is a medical emergency that requires immediate care
  • DKA can develop quickly, often during illness or missed insulin
  • Elevated ketone levels are an early warning sign of DKA
  • Checking ketones can help you act before DKA develops
  • DKA is often preventable with preparation and education 

If you are at risk for DKA, always keep a blood ketone meter or urine ketone strips on hand and check that your supplies are not expired.

You can check for ketones using a blood ketone meter (preferred) or urine ketone strips. If your blood ketone level is 1.6 mmol/L or higher, seek emergency medical care immediately

Symptoms of DKA

DKA symptoms may include:

  • Nausea and vomiting
  • Abdominal pain
  • Rapid or heavy breathing
  • Confusion or difficulty concentrating
  • Extreme fatigue
  • Fruity odor smell
  • Blood glucose (blood sugar) higher than 200 mg/dL (or a level recommended by your doctor)
  • Thirst or very dry mouth
  • Flushed skin

Symptoms can worsen quickly, so early recognition is critical.

What to Do If You Have DKA

DKA is a medical emergency. Get medical help right away if you have symptoms of DKA.

Treatment typically requires:

  • IV fluids
  • Insulin therapy
  • Careful monitoring in a medical setting 

Preventing DKA

You can reduce your risk by:

  • Checking ketones when your blood glucose is high or when you’re sick or not feeling well
  • Following your insulin plan closely
  • Having a sick day or ketone management plan in place
  • Staying hydrated
  • Knowing when to call your care team

Managing ketones early is the most effective way to prevent DKA. Learn how to check and manage ketones.